Metabolism of Biogenic Amines in Acute Cerebral Ischemia: Influence of Systemic Hyperglycemia
نویسنده
چکیده
منابع مشابه
Serum Dopamine-/?-HydroxyIase Activity in Acute Stroke
(Minneap) 25: 483-485, 1975 13. Welch KMA, Chabi E, Buckingham J et al: Catecholamine and 5-hydroxytryptamine levels in ischemic brain. Influence of pchlorophenylalanine. Stroke 8: 341-346, 1977. 14. Welch KMA, Wang T-PF, Chabi E: Ischemia-induced seizures and cortical monoamine levels. Ann Neurol 3: 152-155, 1978 15. Brown RM, Carlson A et al: Effect of ischemia on monoamine metabolism in the ...
متن کاملTargeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells
The organic cation transporters OCT1, 2, and 3 (SLC22A1-3) have been implicated in the elimination of biogenic amines such as histamine. Among them, OCT3 was identified as an uptake-2 transporter, responsible for clearance of histamine. Because increasing evidence suggests the involvement of histamine in cerebral ischemia, we investigated the effects of targeted disruption of organic cation tra...
متن کاملModerate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats.
BACKGROUND AND PURPOSE Clinical and experimental data indicate that hyperglycemia can aggravate the consequences of stroke and cerebral ischemia. The purpose of this study was to examine the effects of moderate hyperglycemia on the response of the blood-brain barrier to normothermic (37 degrees C) and hypothermic (30 degrees C) global forebrain ischemia. METHODS Sixteen rats underwent 20 minu...
متن کاملHyperglycemia in acute ischemic stroke: a vascular perspective.
Admission hyperglycemia complicates approximately one-third of acute ischemic strokes and is associated with a worse clinical outcome. Both human and animal studies have showed that hyperglycemia is particularly detrimental in ischemia/reperfusion. Decreased reperfusion blood flow has been observed after middle cerebral artery occlusion in acutely hyperglycemic animals, suggesting the vasculatu...
متن کاملCerebral blood flow and tissue metabolism in experimental cerebral ischemia of spontaneously hypertensive rats with hyper-, normo-, and hypoglycemia.
The present study was designed to clarify the effect of blood glucose level on cerebral blood flow and metabolism during and after acute cerebral ischemia induced by bilateral carotid ligation (BCL) in spontaneously hypertensive rats (SHR). Blood glucose levels were varied by intraperitoneal infusion of 50% of glucose (hyperglycemia), insulin with hypertonic saline (hypoglycemia) or hypertonic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012